Effects of stellate stimulation and hypoxia on haemodynamics and coronary circulation.

Authors' synopsis The efsects of left stellate ganglion stimulation on haemodynamics and coronary blood flow were studied in dogs, and compared bcirh hypoxia produced by arterial anoxia. Both left stellate stimulation and hypoxia resulted in an increase in coronary blood , f l o ~ , and myocardial oxygen consumption, but the increment in coronary blood flow iz'as much more pronounced during hypoxia. Coronary resistance was signijicantly reduced during hypoxia but not altered during left stellate stimulation. This suggests an inadequate coronary iiasodilator response during lejt stellate stimulation, probably secojidary to a tiasoronstrictor effect of' the sympathetic neroes. This i3asoconstrictor efiect interferes with maximum vasodilatory response to hypoxia that is induced by sympathetic stinrulation.